All Projects

Is there a link between human growth hormone and Creutzfeldt-Jakob disease?

Examining the link between human growth hormone and Creutzfeldt-Jakob disease (CJD)

Cadaveric-derived human growth hormone (HGH) was effective in treating growth failure. Between 1963-85, through the federal government’s National Hormone and Pituitary Program (NHPP), HGH was distributed to 250+ physicians.

In 1985, 3 people who received HGH therapy through the NHPP died of Creutzfeldt-Jakob disease (CJD), a rare neurogenerative disease. These cases prompted the federal government to terminate HGH distribution.

Since then, for the National Institute of Diabetes, Digestive, and Kidney Diseases, Westat has been conducting a surveillance study to identify the scope of the CJD problem in recipients of NHPP-provided hormone. Special attention was paid to whether cases started HGH before or after 1977, when a new laboratory purification step was added.

  • The HGH recipients and their families were located and surveyed.
  • Death certificates, medical records, and pathology specimens were reviewed for evidence of CJD.
  • Through the efforts of this study and reports from other sources, 32 confirmed cases of CJD have been identified among NHPP recipients.
  • No cases began treatment after 1977.
  • Westat continues to analyze and report findings related to CJD and other illnesses.

Want to work with us?
You’ll be in great company.

About Us Careers

Westat Employees.
Westat Employee.
AAA Foundation for Traffic Safety
Baltimore Metropolitan Council
Centers for Disease Control and Prevention
Centers for Medicare & Medicaid Services
Chicago Metropolitan Agency for Planning
DC Public Schools
Georgia Department of Transportation
Internal Revenue Service
Leadership Montgomery
Maryland Cancer Registry
Michigan Department of Health and Human Services
National Science Foundation
NYC Mayor’s Office for Economic Opportunity
Organization for Economic Cooperation and Development
Robert Wood Johnson Foundation
SiriusXM
Social Security Administration
Substance Abuse and Mental Health Services Administration
Teach for America
Texas Education Agency
The Johns Hopkins University
The National Institutes of Health
The Verizon Foundation
Toyota
U.S. Department of Agriculture
U.S. Department of Education
U.S. Department of Health and Human Services
U.S. Department of Justice
U.S. Department of Transportation
U.S. Department of Veterans Affairs
University of Maryland Baltimore Campus
University of Michigan
University System of Maryland
Explore Our Clients

Please wait...

Forbes 2021 The Best Employers for Women Powered by StatistaForbes 2021 The Best Employers for Diversity Powered by StatistaForbes 2021: America's Best Midsize Employer Powered by Statista Forbes 2021 The Best Employers for Veterans Powered by Statista

Westat is an Equal Opportunity Employer and does not discriminate on the basis of race, creed, color, religion, sex, national origin, age, veteran status, disability, marital status, sexual orientation, citizenship status, genetic information, gender identity or expression, or any other protected status under applicable law. Notices to Employees & Applicants.