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Bivalent Boosters Increase Protection Against Severe COVID-19

December 16, 2022

Compared to adults who are unvaccinated or have only received the original mRNA primary series and boosters, adults who received an updated mRNA bivalent booster gained additional protection against COVID-19-associated emergency department/urgent care visits and hospitalizations, based upon a recent analysis from the Centers for Disease Control and Prevention’s (CDC’s) VISION VE project.

The findings appear in the Morbidity and Mortality Weekly Report (MMWR): Early Estimates of Bivalent mRNA Vaccine Effectiveness in Preventing COVID-19–Associated Emergency Department or Urgent Care Encounters and Hospitalizations Among Immunocompetent Adults — VISION Network, Nine States, September–November 2022. These early data suggest that anyone eligible for a bivalent booster should consider receiving their bivalent booster dose.

Westat authors include: Zachary A. Weber, PhD; Sarah E. Reese, PhD; Kristin E. Schrader, MA; Elizabeth A. K. Rowley, DrPH; Margaret M. Dunne, MSc; Yan Zhuang, PhD; Duck-Hye Yang, PhD; and Sarah W. Ball, ScD.


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