Can natural language processing improve the completeness of immunization data?
Harnessing natural language processing to enhance immunization information
Challenge
The VISION surveillance collaboration aims to support public health efforts by routinely collecting and synthesizing respiratory illness data and publishing timely statistical analyses, including vaccine effectiveness (VE).
Surveillance methods often rely on the structured data elements within the electronic health record (EHR) to identify key health characteristics, procedures, and conditions. However, in some instances, details may only be documented in the narrative, text-based sections of the EHR.
Solution
Rule-based natural language processing (NLP) methods have the potential to identify health conditions and procedures using a dictionary of key terms and pattern-matching techniques. We developed NLP rules that leveraged grammatical dependencies within the text and accounted for a range of text variations using a combination of synthetic and publicly available data. Our rules aimed to identify immunizations for respiratory infections, influenza, and respiratory syncytial virus.
We applied the rules to a large sample of individuals from the EHRs of a large health care system and measured performance by conducting a manual review of individual notes, assessing concurrence with structured data, and comparing performance with prior methods.
Results
We were able to identify additional immunizations for respiratory infections, influenza, and RSV that were not present in the structured data. This research demonstrated the feasibility and utility of NLP methods to enhance structured vaccine information from EHRs and served to validate the information contained within the structured EHR data.
Focus Areas
Biomedical Informatics and Data Coordination Clinical Research Disease Surveillance Public HealthCapabilities
Biomedical Informatics and Data Coordination Biostatistics and Epidemiology Data Analytics, Clinical Data Science, and AI Data Collection Data Science and AI EHR Harmonization and Analysis Natural Language Processing and Text Analytics Synthetic Data GenerationSenior Expert Contact
Kevin Wilson
Vice President
-
Perspective
Specialized Support to Promote Innovation in Rural HealthApril 2026
Healthcare providers in rural communities often have more limited access to advanced technologies and digital tools than better-resourced health systems, which can lead to differences…
-
Perspective
Dynamic Guardrails for a Data-Driven World: Inside Westat’s Governance FrameworksMarch 2026
The lightning-fast evolution of technology has demonstrated the critical need for strong governance of information processing. Effective governance frameworks, including policies, standards, and oversight mechanisms…
-
Perspective
How NLP Expands the Power of Clinical NotesFebruary 2026
Electronic health records (EHRs) can capture quantifiable aspects of patient care, such as diagnoses, prescriptions, imaging, and lab test results, all of which are essential…