Experts

Nathan Botts

Principal Research Associate

Overview

Nathan Botts, PhD, is a Principal Research Associate for Clinical Research. With over 17 years of experience, he is an expert in health informatics, clinical systems research, bioinformatics, instructional design, health IT interoperability and standards, and health care cybersecurity.

Botts serves as project director for the HRSA Health Information Technology Evaluation and Quality (HITEQ) Center. His expertise includes electronic health record (EHR) and Health Information Exchange (HIE) adoption, Fast Healthcare Interoperability Resources (FHIR) implementation, electronic patient engagement, and cybersecurity. He has developed extensive resources, conducted training sessions and webinars, and provided technical assistance to federally qualified health centers (FQHCs) and their networks. As the lead developer and administrator of the HITEQ Center’s web platform, he oversees the delivery of over 2,000 training resources, decision support tools, and data visualizations, which have been accessed more than 10 million times under his leadership.

Botts is the IT Project Director for the Electronic Patient Reported Outcomes (ePRO) adoption project for NCI’s Cancer Trials Support Unit (CTSU). In this role, he helps lead the transition of NCI’s patient-reported outcomes (PRO) data collection from paper to an electronic system. Activities within this project include requirements gathering to define an electronic PRO solution integrated with existing NCI electronic data capturing systems and ensuring compliance with federal regulations and security standards. Additionally, he has helped manage software procurement, pilot execution, training, coordinating stakeholders, management of technical specifications, and establishing sustainable support infrastructure aligned with NCI’s clinical trial workflows.

Botts also served as the clinical implementation lead for the CDC’s Making EHR Data More Available for Research and Public Health (MedMorph) project. This initiative employed FHIR-based services for electronic case reporting, enhancing data accessibility for research and public health purposes. Additionally, he led the software engineering efforts for the Early Psychosis Intervention Network’s Web-based Core Assessment Battery (EPINET WebCAB), a NIMH project that supports provider- and patient-facing data collection across 23 psychosis measures. 

Beyond these projects, Botts has contributed as project director for a PCORI-funded telehealth research demonstration project and played a pivotal role in integrating data and developing dashboards for the National Association of Community Health Centers (NACHC/HRSA) Health Center Controlled Network IT Resources Guide. He also provides data analysis and dashboard development for the VA’s Health Information Exchange project, focusing on interoperability measures and national performance evaluation. Botts is Westat’s HL7 standards development representative.

Education

  • PhD, Information Systems and Technology, Claremont Graduate University
  • MS, Information Systems and Technology, Claremont Graduate University
  • MA, Educational Technology, San Diego State University
  • BA, Political Science, University of California, Riverside

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