All Projects

How do you develop a knowledge base for tobacco regulatory science?

Advancing tobacco product regulation through research

To exercise its authority to regulate the manufacture, marketing, and distribution of tobacco products, the Food and Drug Administration (FDA) requires rigorous and timely scientific evidence to inform its regulatory activities. 

The Center for Tobacco Products (CTP) at FDA funds tobacco regulatory science (TRS) research through various mechanisms, including a partnership with the Tobacco Regulatory Science Program (TRSP) at the National Institutes of Health (NIH). The TRSP, within the Office of the NIH Director, oversees the administration of CTP-funded grants throughout various Institutes and Centers at NIH.  Multiple scientific disciplines contribute to developing an extensive knowledge base for the field of TRS. Key areas for research are:

  • Chemical constituents in tobacco products and the methods for measuring them across products
  • Toxicity and carcinogenicity of tobacco products
  • Potential for dependence and addiction of different tobacco products
  • Health effects of tobacco product use
  • Communications about the risks and harms posed by tobacco product use
  • Impact of marketing techniques on susceptibility to tobacco product use
  • Potential impact of FDA regulatory actions

Through a cooperative agreement funded by the FDA's CTP and administered by the National Institute on Drug Abuse, Westat provides support for CTP-funded investigators through the Center for Coordination of Analytics, Science, Enhancement, and Logistics (CASEL) in Tobacco Regulatory Science.  

CASEL is engaged in the following key activities:

  • Acting as a central hub for communications with researchers in the TRS community
  • Creating forums and venues for dissemination of research findings (e.g., through scientific meetings, webinars, and themed special journal issues)
  • Leading initiatives that promote synergies and organized collaborations among researchers in the TRS community (e.g., through topical special interest and working groups)
  • Providing professional development and networking opportunities for TRS trainees and early career scientists
  • Promoting common measures and providing analytical and technical expertise, guidance, and tools

Tobacco regulatory research has contributed to many FDA activities. One example is informing the additional provisions that were in the 2016 “Deeming Rule” that extended FDA’s authority to include the regulation of electronic nicotine delivery systems, all cigars, hookah (waterpipe) tobacco, pipe tobacco, and nicotine gels. 

Research results also informed 2 Advance Notices of Proposed Rulemaking (ANPRMs):

  • Lowering nicotine in cigarettes to a minimally or non-addictive level
  • Regulating flavors in tobacco products, including menthol  

The research supported by CASEL will continue to generate new evidence that informs FDA's tobacco regulatory activities and decisionmaking to positively impact public health.

Want to work with us?
You’ll be in great company.

About Us Careers

Westat Employees.
Westat Employee.
AAA Foundation for Traffic Safety
Baltimore Metropolitan Council
Centers for Disease Control and Prevention
Centers for Medicare & Medicaid Services
Chicago Metropolitan Agency for Planning
DC Public Schools
Georgia Department of Transportation
Internal Revenue Service
Leadership Montgomery
Maryland Cancer Registry
Michigan Department of Health and Human Services
National Science Foundation
NYC Mayor’s Office for Economic Opportunity
Organization for Economic Cooperation and Development
Robert Wood Johnson Foundation
Social Security Administration
Substance Abuse and Mental Health Services Administration
Teach for America
Texas Education Agency
The Johns Hopkins University
The National Institutes of Health
The Verizon Foundation
U.S. Department of Agriculture
U.S. Department of Education
U.S. Department of Health and Human Services
U.S. Department of Justice
U.S. Department of Transportation
U.S. Department of Veterans Affairs
University of Maryland Baltimore Campus
University of Michigan
University System of Maryland
Explore Our Clients

Please wait...

Forbes 2023 America's Best Mid-Size Employers Powered by Statista Forbes 2022 The Best Employers for Women Powered by Statista

Westat is an Equal Opportunity Employer and does not discriminate on the basis of race, creed, color, religion, sex, national origin, age, veteran status, disability, marital status, sexual orientation, citizenship status, genetic information, gender identity or expression, or any other protected status under applicable law. Notices to Employees & Applicants.